Toxicological risk assessment contributing to reduced animal testing.

Predictive toxicology using in silico tools are becoming increasingly important in order to gain time and efficiency in the development of a substance or in the risk assessment before market access. The use of the in silico QSAR approach is encouraged by the REACH regulation 1907/2006/EC and COSMETICS regulation 1223/2009/EC.

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Predictive Toxicology : QSAR based methodology

🔹 Our models are in line with the OECD principles for the QSAR validation, namely :

A well defined category of toxicity
An unambiguous algorithm
A well defined domain of applicability
Statistical criteria about performance

🔹 Today, our Safety By Design approach consists of nine QSAR based statistical models to predict:

Acute toxicity
Carcinogenicity
Mutagenicity
Neurotoxicity
Reprotoxicity
Endocrine disruption
Persistent, bioaccumulative and toxic (PBT) behavior
Respiratory sensitization
Eco-toxicity

🔹 It applies to impurities from the synthesis of pharmaceutical compounds, to your new cosmetic ingredients and botanical extracts, and to specialty chemistry compounds:

A study report allows a categorization of your compounds according to the selected toxicities endpoints required to comply with current regulations and facilitate the commercialization of your product.

Getting benefits right away

✔️ GENERATE TOXICTY ALERTS AT EARLY STAGE

Toxicty alerts could be generated at any stage of a compound development for any of the 9 toxicity endpoints (simultaneously or separately).

✔️ GUIDE IN VITRO & IN VIVO ASSAYS

The data generated as a result of our in silico assessments guide you to select the relevant experimental validations in case of a toxicity alert in line with OECD guidelines.

✔️ COMPLY WITH THE REGULATIONS

The data generated as a result of our in silico assessments contribute to the compliance with the REACH and COSMETICS regulations.

A straightforward rate

Price per compound (excluding VAT)
EVALUATION ON 9 QSAR MODELSAcute toxicity
Carcinogenicity
Mutagenicity
Neurotoxicity
Reprotoxicity
Endocrine disruption
Persistent, bioaccumulative and toxic (PBT) behavior
Respiratory sensitization
Eco-toxicity
9 000€
Reach out

Decision making support

We provide you with a tailor-made support to add value of your products.

How does it work?

To know more, please contact us !